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Charles Runels, MD o-shot providers  was the first person to document the use of platelet rich plasma (PRP) for the purpose of injecting it into the vagina. He coined the term O-shot to describe this procedure. PRP has been described in thousands of research papers demonstrating its ability to rejuvenate tissue in bone and skin. The use of PRP to facilitate post-surgical healing has also been well described. PRP acts by releasing growth factors that in return stimulate the growth of new, healthier tissue. Simply put, PRP forms new blood vessels thus increasing blood flow and stimulates new collagen formation. In addition, serious side effects resulting from injecting an individual’s PRP back into that same person simply have not been reported.

Benefits of the O-Shot

1. Decreases both stress and urge urinary incontinence
2. Increases vaginal lubrication
3. Provides greater arousal from clitoral stimulation
4. Provides stronger orgasms
5. Provides more frequent orgasms
6. Increases sexual desire (libido)
7. Decreases painful intercourse (dyspareunia)
8. Improves Lichen Sclerosis (statistically significant symptom improvement and pathology-confirmed inflammation reduction)

Candidates for the O-Shot

Almost any woman can receive the O-shot. Women both on and off hormone replacement therapy can usually benefit from the procedure. Women with Lichen Sclerosis can benefit. Women suffering from any of the following can benefit from the O-shot…

1. Urinary leakage
2. Dry, painful vagina
3. Low libido/desire
4. Painful intercourse
5. Suboptimal orgasms


1. First, topical numbing cream is applied to the areas to be injected
2. Next, approximately 10cc of blood is drawn from your arm by a very small needle
3. This blood is prepared for use
4. While the blood is being prepared, the clitoris is numbed using a tiny needle with little to no pain
5. The PRP is then isolated and activated
6. Approximately 4cc of activated PRP is injected into the O spot (just inside the vaginal opening on the top wall)
7. The remaining 1cc of activated PRP is injected into the body of the clitoris (again with little to no pain)

The entire procedure takes around 30 minutes to complete.

When Do You Notice the Benefits?

Occasionally, women will experience an immediate, transient period of hyper arousal and hyper sexuality. Typically however, women will begin to get a tissue response in three weeks. At the three-month mark, women will achieve maximum benefit.

How Long Does the O-Shot Last?

Up to three years. However, some women may choose to have it performed much more frequent. Click the button bellow to see our pricing on O-Shot and other AGD – Services.